The rise in popularity of GLP-1 medications is largely because patients have seen impressive results after staying on a regimen long term, alongside healthy lifestyle practices. Medications like semaglutide, tirzepatide, and retatrutide silence the persistent “food noise” that many patients experience, helping them feel fuller with smaller meal portions. (1)
Though each of these medications has its differences, they all belong to a class of drugs known as GLP-1 receptor agonists, which means they imitate a hormone in the body called glucagon-like peptide-1. This hormone plays a role in insulin sensitivity, blood sugar control, and appetite suppression.
If you would like to explore more about how a specialized GLP-1 regimen can help you achieve your weight loss goals, please reach out to schedule a consultation with Dr. Christopher Asandra. Dr. Asandra is one of Beverly Hills’ leading hormone health and weight management experts, and his personalized care plans have helped improve the lives and health of countless patients. Schedule your consultation today by completing our online inquiry form.
If you have any further questions, please feel free to call our Beverly Hills or Newport Beach offices at (424) 542-8881 or (949) 200-8317, respectively.
About GLP-1 Medications
Weight gain is often associated with various health risks like diabetes, high blood pressure, and heart disease. (2) The introduction of GLP-1 medications marks a breakthrough in weight loss, offering new hope for those who have struggled with their weight. There are two main GLP-1 medications available—semaglutide and tirzepatide—with others, like retatrutide, currently being researched.
Clinical trials have shown impressive results, showcasing significant weight loss among participants. These medications are delivered via subcutaneous injection. (2)
Semaglutide
Semaglutide is only a GLP-1 receptor agonist, meaning that it only targets this hormone, unlike tirzepatide and retatrutide.
Tirzepatide
Tirzepatide is a dual agonist medication that targets both the GLP-1 hormone receptors and the glucose-dependent insulinotropic polypeptide (GIP) hormone receptors.
Retatrutide
Retatrutide is an investigational medication that is projected to be a triple agonist medication that targets the GLP-1, GIP, and glucagon hormone receptors.
Uses of GLP-1s Beyond Weight Loss
These medications have also shown promising benefits beyond blood sugar control and weight loss. In Alzheimer’s disease, GLP-1s have been researched for reducing brain inflammation, improving insulin signaling, and protecting neurons, all of which might potentially slow cognitive decline. (3) They have also been shown to improve kidney disease, especially diabetic nephropathy, by reducing albuminuria and slowing the progression of kidney damage. (4)
They may also have cardiovascular benefits, including reduced risk of heart attack and stroke. This is thought to come as an addition to weight reduction, but it is also likely due to reduced inflammation and improved blood flow. GLP-1 agonists possess anti-inflammatory properties, which might help address a multitude of diseases. Research is still ongoing, but GLP-1s have promising potential for numerous treatments beyond weight loss.
Personal Consultation
The first step in starting a GLP-1 regimen involves a personal consultation with a specialist. During this meeting, Dr. Asandra will review your medical history and discuss your weight loss goals and past efforts. He will evaluate your overall health, including any underlying conditions that could affect your eligibility to take GLP-1s.
After discussing all treatment options, Dr. Asandra will answer any questions you may have regarding these medications and their potentially transformative effects. Your comfort and understanding will be top priorities throughout the process.
Schedule your consultation today by submitting our online contact form or by calling our Beverly Hills or Newport Beach offices at (424) 542-8881 or (949) 200-8317, respectively.
Procedure
GLP-1 medications are administered through weekly subcutaneous injections. Other methods are currently being researched, but as of 2025, only injection is available. Your dosage may vary depending on your weight loss goals, medical needs, current weight, exercise and diet habits, and more. (2)
Areas for these subcutaneous injections include the abdomen, thigh, or upper arm. After injecting the medication, you can return to your normal activities immediately. However, some patients might experience an adjustment period in the early stages of their regimen, during which they might want to schedule some downtime.
GLP-1s vs. Traditional Methods
Traditional methods of weight loss include exercise, dieting, and bariatric surgery. While some patients find success with these methods, many find these methods unsustainable or inadequate. Meanwhile, many patients have achieved great results while on a GLP-1 medication because of the way the medications actually inhibit recurring cravings.
It is important to note that exercise and dieting should not be ignored while on a GLP-1 regimen. Patients should commit to a healthy lifestyle, as this will not only help them achieve the best results possible, but it will also ensure that patients are physically healthy and getting the right nutrients.
Recovery
While adjusting to their medications, some patients may experience mild side effects such as nausea, vomiting, or diarrhea, especially during the initial weeks. These symptoms typically fade over time as the body adjusts to the medication. They can also be managed with antacid tablets and over-the-counter medications. Staying hydrated is also helpful in mitigating these side effects. Regular follow-up appointments with Dr. Asandra will monitor progress and offer ongoing support throughout your treatment plan.
Results
Many individuals start noticing results within the first few months of starting their medications, with continued improvement over time. Achievable results include substantial weight loss, a greater sense of fullness after consuming smaller portions, and better management of blood glucose levels. Patients see a 5-6% loss of weight within their first month of treatment, with this number only increasing with consistent use. (5)
Consistency in following the prescribed treatment plan, engaging in physical activity, and practicing healthier eating habits will enhance your overall outcome. Long-term success hinges on commitments to lifestyle modifications in conjunction with treatment.
After achieving weight loss results, patients can continue to stay on the medication with a maintenance dose, or they can stop the medication altogether. If a patient ceases the medication, there is a risk of weight regain, as cravings do return. Continuing to live a healthy lifestyle after ceasing GLP-1 medication can help patients maintain their results while prioritizing the longevity of their health.
Cost of GLP-1 Medications in Beverly Hills
The total cost of your weight loss medication regimen will depend on the dosages required in your treatment, how long you remain on the medication, and a few other factors. After you meet with Dr. Asandra, you will receive a cost estimate for your treatment.
To take the next step in your weight loss journey, please schedule a consultation today by completing our online inquiry form. If you have any further questions, please call our Beverly Hills or Newport Beach offices at (424) 542-8881 or (949) 200-8317, respectively.
FAQ
What are the side effects of GLP-1 medications?
Common side effects may include nausea, vomiting, diarrhea, and stomach pain. Most individuals find that these side effects lessen as they continue treatment. Staying hydrated may help mitigate these side effects.
How long should I stay on GLP-1s?
Individuals may stay on a GLP-1 regimen as long as they want, typically in the form of a maintenance dose after weight loss results have been achieved. In clinical trials, patients stayed on the medication for over a year and saw significant changes in their weight.
Can GLP-1s be stopped abruptly?
It is crucial to discuss any changes in your treatment regimen with Dr. Asandra rather than making sudden decisions, as doing so may impact your health. Dr. Asandra can help guide you through the process of stopping GLP-1 medications.
Are GLP-1s safe for everyone?
While they are generally considered safe when taken under the guidance of a certified professional, they may not be suitable for individuals with certain medical histories or conditions. A consultation with your doctor will help identify any potential risks.
Can GLP-1 medications replace dieting and exercising?
No, these medications are intended to complement a balanced diet and an active lifestyle to promote optimal weight management and health. Patients should continue to make healthy choices while on the medication.
References
- Hayashi D, Edwards C, Emond JA, et al. What Is Food Noise? A Conceptual Model of Food Cue Reactivity. Nutrients. 2023;15(22):4809-4809. doi:https://doi.org/10.3390/nu15224809
- Kommu S, Whitfield P. Semaglutide. PubMed. Published February 11, 2024. https://www.ncbi.nlm.nih.gov/books/NBK603723/
- Fessel J. All GLP-1 Agonists Should, Theoretically, Cure Alzheimer’s Dementia but Dulaglutide Might Be More Effective Than the Others. Journal of Clinical Medicine. 2024;13(13):3729-3729. doi:https://doi.org/10.3390/jcm13133729
- Perkovic V. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes. New England journal of medicine/˜The œNew England journal of medicine. 2024;391(2). doi:https://doi.org/10.1056/nejmoa2403347
- Ghusn W, De la Rosa A, Sacoto D, et al. Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity. JAMA Network Open. 2022;5(9):e2231982. doi:https://doi.org/10.1001/jamanetworkopen.2022.31982